Glucagon is secreted by alpha cells in the pancreas in response to what condition?

• A. High blood glucose
• B. Low blood glucose
• C. High blood pressure
• D. Low blood pressure

Answer: (B)

Glucagon is secreted by the alpha cells of the pancreas primarily in response to low blood glucose levels. When blood glucose levels drop, glucagon is released to help increase those levels. It triggers the liver to convert stored glycogen into glucose, which is then released into the bloodstream, thereby raising blood sugar levels. This action is crucial for maintaining energy homeostasis in the body, particularly during fasting states or between meals when glucose levels can decline.

In contrast, high blood glucose triggers the secretion of insulin, and neither blood pressure options directly pertain to glucagon release. Thus, understanding the relationship between glucagon and blood glucose levels highlights its critical role in metabolic regulation.